Alyssa Milano is an American actress, producer, entrepreneur, and philanthropist. She is best known for portraying Samantha Micelli on the ABC sitcom series Who's the Boss? (1984–1992), Jennifer Mancini on the Fox soap opera Melrose Place (1997–98), and Phoebe Halliwell on The WB television series Charmed.. Milano is currently working with. UNICEF to educate American youth to the issues crucial to that country's evolution. She launched UNICEF's pivotal "Trick or Treat" campaign last fall as an official spokesperson, and has plans to work with UNICEF on numerous projects in the future, with any and all proceeds returning to the organization.. Milano also has her own clothing and jewelry line, TOUCH by Alyssa Milano. Recently she has joined forces with the NFL, NBA and NHL to make TOUCH available to fans of football, basketball and hockey as well.